| References: |
Apoptosis Activator 2 is a cell-permeable indoledione compound that activates caspases in a cytochrome c-dependent manner and induces apoptosis in tumor cells by promoting the oligomerization of Apaf-1 into the mature apoptosome. Its cytotoxicity is selective towards tumor cells (IC50 < 10 μM For Jurkat, Molt-4, and CCRF-CEM). Apoptosis Activator 2 shows little or no effect on non-tumor cells or cells that are deficient in caspase-3 or Apaf-1. Apoptosis Activator 2 is an activator of caspase-3.
For the detailed information about the solubility of Apoptosis Activator 2 in water, the solubility of Apoptosis Activator 2 in DMSO, the solubility of Apoptosis Activator 2 in PBS buffer, the animal experiment（test） of Apoptosis Activator 2 , the in vivo,in vitro and clinical trial test of Apoptosis Activator 2 , the cell experiment（test） of Apoptosis Activator 2 , the IC50, EC50 and Affinity of Apoptosis Activator 2 , please contact DC Chemicals. |
