ICG-001
产品编号: DC3130
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应用领域
ICG-001 是一种 Wnt/β-catenin/TCF -介导的转录拮抗剂,特别结合元件结合蛋白 (CBP),IC50 值为 3 μM。
Cas No.: |
780757-88-2 |
名称: |
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别名: |
ICG001,ICG 001 |
SMILES: |
C1CN([C@H]2CN(C(=O)[C@@H](N2C1=O)CC3=CC=C(C=C3)O)CC4=CC=CC5=CC=CC=C54)C(=O)NCC6=CC=CC=C6 |
分子式: |
C33H32N4O4 |
分子量: |
548.63 |
纯度: |
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保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: |
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In Vivo: |
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In Vitro: |
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References: |
ICG-001 antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to element-binding protein (CBP) with IC50 of 3 μM, but is not the related transcriptional coactivator p300.
IC50 value: 3 uM
Target: Wnt
in vitro: ICG-001 has no effect o |
Kinase Assay: |
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Cell Assay: |
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Animal Administration: |
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References: |
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MSDS
COA
LOT NO. |
DOWNLOAD |
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2018-0101 |
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