| Cas No.: | 778270-11-4 |
| 名称: | Benzamide, 3-[6-[[4-(trifluoromethoxy)phenyl]amino]-4-pyrimidinyl]- |
| 别名: | GNF2,GNF 2 |
| SMILES: | C1=CC(=CC(=C1)C(=O)N)C2=CC(=NC=N2)NC3=CC=C(C=C3)OC(F)(F)F |
| 分子式: | C18H13F3N4O2 |
| 分子量: | 374.32 |
| 纯度: | |
| 保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | |
| In Vivo: | |
| In Vitro: | |
| References: | Description of GNF-2: GNF-2 is an allosteric inhibitor of Bcr-abl tyrosine kinase activity (IC50 = 267 nM); inhibits proliferation and induces apoptosis in Bcr-abl-expressing cells. Selective For Bcr-abl over a panel of serine, threonine and tyrosine kinases. Non-ATP-competitive. For the detailed information about the solubility of GNF-2 in water, the solubility of GNF-2 in DMSO, the solubility of GNF-2 in PBS buffer, the animal experiment（test） of GNF-2,the in vivo,in vitro and clinical trial test of GNF-2,the cell experiment（test） of GNF-2,the IC50, EC50 and Affinity of GNF-2, please contact DC Chemicals. |
| Kinase Assay: | |
| Cell Assay: | |
| Animal Administration: | |
| References: |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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