OSU-03012
产品编号: DC7220
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应用领域
OSU-03012(AR-12) is a potent inhibitor of recombinant PDK-1 with IC50 of 5 μM and 2-fold increase in potency over OSU-02067.
Cas No.: |
742112-33-0 |
名称: |
2-amino-N-(4-(5-(phenanthren-2-yl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)phenyl)acetamide |
别名: |
AR-12; OSU03012; OSU 03012 |
SMILES: |
O=C(CN)NC1=CC=C(C=C1)N2N=C(C=C2C3=CC=C4C5=CC=CC=C5C=CC4=C3)C(F)(F)F |
分子式: |
C26H19F3N4O |
分子量: |
460.45 |
纯度: |
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保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: |
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In Vitro: |
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References: |
OSU-03012 induces apoptotic death in PC-3 cells with IC50 of 5 µM and reduces the activity of immunoprecipitated p70S6K. OSU-03012 completely suppress cell growth in a diverse range of tumor cell lines at concentrations of 3–5 μm, as compared with the con |
Kinase Assay: |
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Cell Assay: |
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Animal Administration: |
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References: |
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MSDS
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DOWNLOAD |
MSDS_3106_DC7220_742112-33-0 |
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COA
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