AZD1152 (barasertib)
产品编号: DC7060
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应用领域
AZD1152 是 Barasertib-hQPA 的前体药物，是高度选择性的 Aurora B 抑制剂，IC50 值为 0.37 nM。
| Cas No.: |
722543-31-9 |
| 名称: |
2-[ethyl-[3-[4-[[5-[2-(3-fluoroanilino)-2-oxoethyl]-1H-pyrazol-3-yl]amino]quinazolin-7-yl]oxypropyl]amino]ethyldihydrogenphosphate |
| 别名: |
Barasertib; AZD-1152; AZD 1152 |
| SMILES: |
CCN(CCCOC1=CC2=C(C=C1)C(=NC=N2)NC3=NNC(=C3)CC(=O)NC4=CC(=CC=C4)F)CCOP(=O)(O)O |
| 分子式: |
C26H31FN7O6P |
| 分子量: |
587.539805 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| References: |
AZD1152 (barasertib)is the pro-drug of barasertib-hQPA, An orally bioavailable, small-molecule, dihydrogen phosphate prodrug of the pyrazoloquinazoline Aurora kinase inhibitor AZD1152–hydroxyquinazoline pyrazol anilide (AZD1152-HQPA) with potential antine |
| Kinase Assay: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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