BMS-599626 (AC480)
产品编号: DC3105
我们的合作伙伴:
中国地区超过5000个高品质化合物库存
应用领域
BMS-599626 (AC480) is a selective and efficacious inhibitor of HER1 and HER2 with IC50 of 20 nM and 30 nM, respectively.
Cas No.: |
714971-09-2 |
名称: |
(S)-morpholin-3-ylmethyl 4-(1-(3-fluorobenzyl)-1H-indazol-5-ylamino)-5-methylpyrrolo[1,2-f][1,2,4]triazin-6-ylcarbamate |
别名: |
BMS599626,AC-480, BMS 599626 (AC480) |
SMILES: |
O=C(NC1=CN2C(C(NC3=CC4=C(N(CC5=CC=CC(F)=C5)N=C4)C=C3)=NC=N2)=C1C)OC[C@H]6NCCOC6 |
分子式: |
C27H27FN8O3.HCl |
分子量: |
567.01 |
纯度: |
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保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: |
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In Vitro: |
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References: |
BMS-599626 is an orally bioavailable inhibitor of the HER1, HER2 and HER4 tyrosine kinases (IC50=22, 32 and 190 nM, respectively) with potential antineoplastic activity. BMS-599626 inhibits human epidermal growth factor receptors (HER) HER1, HER2 and HER4 |
Kinase Assay: |
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Cell Assay: |
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Animal Administration: |
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References: |
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MSDS
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MSDS_3362_DC3105_714971-09-2 |
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