Cas No.: | 677297-51-7 |
名称: | 6,7-Bis(3-hydroxyphenyl)pteridine-2,4-diamine |
别名: | TG100115; TG100 115 |
SMILES: | NC1=C(C(N=C2C3=CC(O)=CC=C3)=NC(N)=N1)N=C2C4=CC(O)=CC=C4 |
分子式: | C18H14N6O2 |
分子量: | 346.34 |
纯度: | |
保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | |
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In Vitro: | |
References: | TG100-115 inhibits PI3Kγ and -δ, with IC50 of 83 and 235 nM, respectively. TG100-115 is not active For PI3Kα and -β, with IC50 of 1.2 and 1.3 mM. In human umbilical vein endothelial cells (HUVECs), TG100-115 (up to 10 μM) has no effects on cell prolifera |
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Animal Administration: | |
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