Vicriviroc maleate(Sch-417690)
产品编号: DC7336
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应用领域
Vicriviroc maleate (SCH-417690 maleate; SCH-D maleate) 是一种有效，选择性，可口服，可透过血脑屏障的 CCR5 拮抗剂，Ki 值为 2.5 nM，同时抑制外周血单核细胞中的 HIV-1 的活性，IC90 值分别为 3.3 nM (JrFL)，2.8 nM (ADA-M)，1.8 nM (301657)，4.9 nM (JV1083) 和 10 nM (RU 570)。
| Cas No.: |
599179-03-0 |
| 名称: |
(4,6-dimethylpyrimidin-5-yl)-[4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methylpiperazin-1-yl]-4-methylpiperidin-1-yl]methanone;2-hydroxybutanedioicacid |
| 别名: |
Sch 417690,Sch417690 |
| SMILES: |
N(C(C1=C(C)N=CN=C1C)=O)1CCC(N2CCN([C@@H](C3=CC=C(C(F)(F)F)C=C3)COC)[C@H](C)C2)(C)CC1.C(O)(=O)/C=C/C(O)=O |
| 分子式: |
C32H42F3N5O6 |
| 分子量: |
649.7 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| References: |
Vicriviroc, previously named SCH 417690 and SCH-D, is a pyrimidine CCR5 entry inhibitor of HIV-1. For the detailed information of Vicriviroc maleate(Sch-417690), the solubility of Vicriviroc maleate(Sch-417690) in water, the solubility of Vicriviroc malea |
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| References: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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