Cas No.: | 56296-18-5 |
名称: | |
别名: | |
SMILES: | C1CN(CCN1)C2=NC3=CC=CC=C3NC4=CC=CC=C42 |
分子式: | C17H18N4 |
分子量: | 278.4 |
纯度: | |
保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | |
In Vivo: | |
In Vitro: | |
References: | DREADD agonist 21 activates hM3Dq (EC50 = 1.7 nM), a designer receptor exclusively activated by designer drugs (DREADD) derived from the human muscarinic acetylcholine M3 receptor.It does not agonize the hM3 receptor and displays relatively weaker binding affinities for serotonin 5HT2A, 5HT2C, α1A-adrenergic, and histamine H1 receptors (Kis = 66, 170, 280, and 6 nM, respectively). |
Kinase Assay: | |
Cell Assay: | |
Animal Administration: | |
References: |