A-674563
产品编号: DC5163
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应用领域
A-674563是有效，选择性的 Akt1 抑制剂，Ki为11 nM。
| Cas No.: |
552325-73-2 |
| 名称: |
(S)-1-((5-(3-methyl-1H-indazol-5-yl)pyridin-3-yl)oxy)-3-phenylpropan-2-amine |
| 别名: |
A-674563; A 674563; A674563 |
| SMILES: |
C(OC1=CC(C2C=CC3=C(C=2)C(C)=NN3)=CN=C1)[C@H](N)CC1=CC=CC=C1 |
| 分子式: |
C22H22N4O |
| 分子量: |
358.43 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
A-674563 is a potent selective Akt1 (Protein Kinase B) inhibitor (IC50 = 14 nM). A-674563 also shows inhibitory activity against PKA and Cdk2 (IC50’s: PKA = 16 nM; Cdk2 = 46 nM). A-674563 has been shown to have a significant effect on depolarization of pu |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_1456_DC5163_552325-73-2 |
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COA
| LOT NO. |
DOWNLOAD |
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询盘
