Tasisulam(LY573636)
产品编号: DC7312
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应用领域
Tasisulam 是一种小分子抗肿瘤药物，通过内在途径诱导细胞凋亡，导致细胞色素 c 释放和 caspase 依赖性细胞死亡。Tasisulam 可以抑制有丝分裂进程并诱导血管正常化。
| Cas No.: |
519055-62-0 |
| 名称: |
Benzamide,N-[(5-bromo-2-thienyl)sulfonyl]-2,4-dichloro- |
| 别名: |
LY573636-sodium; benzamide |
| SMILES: |
C1=CC(=C(C=C1Cl)Cl)C(=O)NS(=O)(=O)C2=CC=C(S2)Br |
| 分子式: |
C11H6BrCl2NO3S2 |
| 分子量: |
415.11 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
Tasisulam inhibits growth of various human leukemia and lymphoma cell lines with ED50 ranging from 7 to 40 μM. LY573636 also induces apoptosis in HL60, Reh, and MD901 cells, mainly by loss of mitochondrial membrane potential and induction of reactive oxyg |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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询盘
