| DC20000 |
LR-90
|
LR-90 is an advanced glycation end product (AGE) inhibitor, inhibits inflammatory responses in human monocytes. LR-90 is also used in the research of diabetic animal model. |
| DC26231 |
Furin Inhibitor II
|
Hexa-D-arginine (Furin Inhibitor II) 是一种稳定的 furin 抑制剂，对 furin，PACE4 和 PC1 的 Ki 值分别为 106 nM，580 nM 和 13.2 μM。Hexa-D-arginine 在体外和体内均可阻断假单胞菌外毒素 A 和炭疽毒素的毒性。 |
| DC21672 |
SNAP-94847 hydrochloride
|
SNAP 94847 是一种新型的，高亲和力的选择性黑色素浓缩激素受体 1 (MCHR1) 拮抗剂，其 (Ki= 2.2 nM, Kd=530 pM)，它对 MCHα1A 和 MCHD2 受体分别显示出 >80 倍和 >500 倍的选择性。 SNAP 94847 以高亲和力与小鼠和大鼠 MCHR1 结合，与其他 GPCR，离子通道，酶和转运蛋白的交叉反应性很小。 |
| DC8759 |
Thiamet G
|
Thiamet G is a potent and selective inhibitor of O-GlcNAcase that demonstrates a Ki value of 21 nM. |
| DC9619 |
Nafamostat (mesylate)
|
Nafamostat mesylate, a synthetic serine protease inhibitor, is an anticoagulant,showed highly potent activity against COVID-19(SARS-COV-2). |
| DC8729 |
Bifeprunox
|
Bifeprunox is a Dopamine D2 and 5-HT1A partial agonist in development as a potential treatment for schizophrenia and other psychotic indications. |
| DC7992 |
PX 12
|
PX-12(IV-2) is an irreversible inhibitor of Thioredoxin-1(Trx-1) currently in clinical development as an antitumor agent; IC50=7 uM in Hela, MTT assay, 72 h. |
| DC7773 |
BNC-105
|
BNC105 is a novel tubulin polymerization inhibitor that selectively disrupts tumor vasculature and displays single-agent antitumor efficacy. |
| DC7229 |
PF-4708671
|
PF-4708671 is a novel cell-permeable inhibitor of S6K1 (p70 ribosomal S6 kinase 1), with a Ki of 20 nM and IC50 of 160 nM. |
| DC28714 |
FK962
|
FK962 is an enhancer of somatostatin release, exerts cognitive-enhancing actions. Anti-dementia properties. |
