CIQ

产品编号: DC8156 Featured
CIQ
结构式
486427-17-2
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中国地区超过5000个高品质化合物库存
应用领域
CIQ是一种亚基选择性的NMDA受体增强剂, 作用于NR2C或NR2D亚基。
Cas No.: 486427-17-2
名称: (3-Chlorophenyl) [3,4-dihydro-6,7-dimethoxy-1-[(4-methoxyphenoxy)methyl]-2(1H)-isoquinolinyl]methanone
别名:
SMILES: COC1=CC=C(C=C1)OCC2C3=CC(=C(C=C3CCN2C(=O)C4=CC(=CC=C4)Cl)OC)OC
分子式: C26H26ClNO5
分子量: 468
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: A positive allosteric modulator selective for NR2C/D containing NMDA receptors (EC50 = 2.7 and 2.8 µM for NR2C and NR2D, respectively). Increases channel opening frequency of recombinant NR2C/D containing NMDA receptors by two-fold without altering mean open time or EC50 values for glutamate or glycine bindings. No effect on NR2A or NR2B subtypes. For the detailed information of CIQ, the solubility of CIQ in water, the solubility of CIQ in DMSO, the solubility of CIQ in PBS buffer, the animal experiment (test) of CIQ, the cell expriment (test) of CIQ, the in vivo, in vitro and clinical trial test of CIQ, the EC50, IC50,and affinity,of CIQ, For the detailed information of CIQ, the solubility of CIQ in water, the solubility of CIQ in DMSO, the solubility of CIQ in PBS buffer, the animal experiment (test) of CIQ, the cell expriment (test) of CIQ, the in vivo, in vitro and clinical trial test of CIQ, the EC50, IC50,and affinity,of CIQ, Please contact DC Chemicals.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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