Cas No.: | 459868-92-9 |
名称: | |
别名: | AG-14699 (as phosphate salt), AG-014447 (as free base); Rucaparib; PF-01367338; AG014699; |
SMILES: | CNCC1=CC=C(C=C1)C2=C3CCNC(=O)C4=CC(=CC(=C34)N2)F.OP(=O)(O)O |
分子式: | C19H18FN3O.H3Po4 |
分子量: | 421.36 |
纯度: | |
保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | |
In Vivo: | |
In Vitro: | |
References: | Rucaparib (AG-14699 or PF-01367338) is a tricyclic indole poly(ADP-Ribose) polymerase (PARP1) inhibitor with potential chemosensitizing, radiosensitizing, and antineoplastic activities. Rucaparib selectively binds to PARP1 and inhibits PARP1-mediated DNA |
Kinase Assay: | |
Cell Assay: | |
Animal Administration: | |
References: |