ITE

产品编号: DC8318 Featured
ITE
结构式
448906-42-1
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中国地区超过5000个高品质化合物库存
应用领域
ITE 是一种有效的内源性芳香烃受体 (AhR) 激动剂,能够直接与 AHR 结合,Ki 值为 3 nM。ITE 具有免疫抑制作用。
Cas No.: 448906-42-1
名称: 2-(1H-Indol-3-ylcarbonyl)-4-thiazolecarboxylic acid methyl ester
别名: Aryl hydrocarbon receptor ligand
SMILES: S1C=C(C(OC)=O)N=C1C(C1C2=C(NC=1)C=CC=C2)=O
分子式: C14H10N2O3S
分子量: 286.3
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: Endogenous aryl hydrocarbon receptor (AhR) agonist (Ki = 3 nM). Decreases Oct4 levels in U87 glioblastoma cells. Induces stem-like cancer cell differentiation in U87 tumor spheres in vitro and suppresses tumor growth in U87 cell xenografts in mice. Also inhibits TGF-β-induced human myofibroblast differentiation. For the detailed information of ITE, the solubility of ITE in water, the solubility of ITE in DMSO, the solubility of ITE in PBS buffer, the animal experiment (test) of ITE, the cell expriment (test) of ITE, the in vivo, in vitro and clinical trial test of ITE, the EC50, IC50,and affinity,of ITE, For the detailed information of ITE, the solubility of ITE in water, the solubility of ITE in DMSO, the solubility of ITE in PBS buffer, the animal experiment (test) of ITE, the cell expriment (test) of ITE, the in vivo, in vitro and clinical trial test of ITE, the EC50, IC50,and affinity,of ITE, Please contact DC Chemicals.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
TITLE DOWNLOAD
MSDS_2266_DC8318_448906-42-1
COA
LOT NO. DOWNLOAD
产品编号 产品名称 应用领域
DC8318 ITE ITE 是一种有效的内源性芳香烃受体 (AhR) 激动剂,能够直接与 AHR 结合,Ki 值为 3 nM。ITE 具有免疫抑制作用。
DC7939 CH-223191 CH-223191 是芳烃受体 (AhR) 的有效特异性拮抗剂。 CH-223191 抑制 TCDD 介导的核转位和 AhR 的 DNA 结合。CH-223191 抑制 TCDD 诱导的荧光素酶活性的 IC50 值为 0.03 μM。