Genistein

产品编号: DC2092 Featured
Genistein
结构式
446-72-0
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中国地区超过5000个高品质化合物库存
应用领域
Genistein是一种大豆异黄酮,是一种多重的酪氨酸激酶 (tyrosine kinases,比如 EGFR) 抑制剂,是对多种癌症的化疗剂,主要通过改变细胞凋亡 (apoptosis),细胞周期和血管生成以及抑制转移。
Cas No.: 446-72-0
名称: 5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one
别名:
SMILES: C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)O)O
分子式: C15H10O5
分子量: 270.24
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: Genistein, a phytoestrogen found in soy products, is a highly specific inhibitor of protein tyrosine kinase (PTK) which blocks the mitogenic effect mediated by EGF on NIH-3T3 cells with IC50 of 12μM or by insulin with IC50 of 19 μM. For the detailed information about the solubility of Genistein in water, the solubility of Genistein in DMSO, the solubility of Genistein in PBS buffer, the animal experiment(test) of Genistein,the in vivo,in vitro and clinical trial test of Genistein,the cell experiment(test) of Genistein,the IC50, EC50 and Affinity of Genistein, please contact DC Chemicals.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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