ML367

产品编号: DC26162 Featured
ML367
结构式
381168-77-0
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中国地区超过5000个高品质化合物库存
应用领域
ML367 是一种 ATPase 家族 AAA 结构域蛋白 5 (ATAD5) 稳定的有效抑制剂,作为一个探针分子,具有低摩尔抑制浓度。ML367 阻断 DNA 的修复通路,抑制一般的 DNA 损伤反应,包括应对紫外照射产生的 RPA32 和 CHK1 的磷酸化。
Cas No.: 381168-77-0
名称:
别名: ML367,ML 367,ML-367
SMILES: FC1=CC(NC2=NC(C3=CC=NC=C3)=NC4=CC=CC=C42)=CC=C1F
分子式: C19H12F2N4
分子量: 334.32
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: ML367 is a potent inhibitor of ATPase family AAA domain-containing protein 5 (ATAD5) stabilization, acts as a probe molecule that has low micromolar inhibitory activity. ML367 blocks DNA repair pathways, suppresses general DNA damage responses including R
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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