Cas No.: | 36945-98-9 |
名称: | 3,6-dihydro-1-(2-hydroxyphenyl)-4-(3-nitrophenyl)-2(1H)-pyrimidinone |
别名: | AG 3-5; AG-3-5 |
SMILES: | C(=O)1N(C2=CC=CC=C2O)CC=C(C2=CC=CC([N+]([O-])=O)=C2)N1 |
分子式: | C16H13N3O4 |
分子量: | 311.3 |
纯度: | |
保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | |
In Vivo: | |
In Vitro: | |
References: | Nociceptive sensory peripheral neurons often express both heat sensitive (VR1) and cold-sensitive (CMR1 (rat); TRPM8 (human)) receptors that are part of the transient receptor potential (TRP) superfamily. Icilin (AG 3-5) is a synthetic CMR1/TRPM8 super ag |
Kinase Assay: | |
Cell Assay: | |
Animal Administration: | |
References: |