Balicatib
产品编号: DC7371
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应用领域
Balicatib(AAE-581)是组织蛋白酶K抑制剂,比对组织蛋白酶B,L和S的抑制性高10到100倍。
Cas No.: |
354813-19-7 |
名称: |
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别名: |
AAE581; AAE 581; AAE-581 |
SMILES: |
C(NC(C(=O)NCC#N)1CCCCC1)(=O)C1=CC=C(N2CCN(CCC)CC2)C=C1 |
分子式: |
C23H33N5O2 |
分子量: |
411.54 |
纯度: |
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保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: |
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In Vivo: |
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In Vitro: |
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References: |
Balicatib(AAE-581) is a potent and selective inhibitor of cathepsin K; 10-100-fold more potent in cell-based enzyme occupancy assays than against cathepsin B, L, and S.
IC50 value:
Target: cathepsin K
The cathepsin K inhibitor AAE-581 (balicatib) as the m |
Kinase Assay: |
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Cell Assay: |
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Animal Administration: |
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References: |
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MSDS
COA
LOT NO. |
DOWNLOAD |
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2018-0101 |
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