Cas No.: | 342639-96-7 |
名称: | |
别名: | KRIBB 11,KRIBB-11 |
SMILES: | CNC1=NC(=C(C=C1)[N+](=O)[O-])NC2=CC3=C(C=C2)NN=C3 |
分子式: | C13H12N6O2 |
分子量: | 284.27 |
纯度: | |
保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | |
In Vivo: | |
In Vitro: | |
References: | Heat shock factor (HSF) inhibitor (IC50 = 1.2 μM). Increases apoptosis in cancer cells treated with the HSP90 inhibitors Geldanamycin and 17-AAG. Blocks downstream induction of HSP27 and HSP70. Inhibits tumor growth in vivo. |
Kinase Assay: | |
Cell Assay: | |
Animal Administration: | |
References: |