Cas No.: | 34157-83-0 |
名称: | (2R,4aS,6aS,12bR,14aS,14bR)-10-hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydropicene-2-carboxylic acid |
别名: | |
SMILES: | C1[C@]([H])2[C@](C)(CC[C@@](C)3[C@]2(C)CC[C@](C)2C3=CC=C3C2=CC(=O)C(O)=C3C)CC[C@]1(C)C(O)=O |
分子式: | C29H38O4 |
分子量: | 450.61 |
纯度: | |
保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | |
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In Vitro: | |
References: | Antioxidant and anti-inflammatory agent. Potently inhibits lipid peroxidation in mitochondria and inhibits TNF-α-induced NFκB activation. Also shown to inhibit topoisomerase II activity in vitro (IC50 = 7.41 μM). For the detailed information of Celastrol, the solubility of Celastrol in water, the solubility of Celastrol in DMSO, the solubility of Celastrol in PBS buffer, the animal experiment(test) (test) of Celastrol, the cell expriment (test) of Celastrol, the in vivo, in vitro and clinical trial test of Celastrol, the EC50, IC50,and Affinity of Celastrol,, please contact DC Chemicals. |
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Cell Assay: | |
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