CFTR Inhibitor II
产品编号: DC7039
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应用领域
GlyH-101是可渗透入细胞的CFTR阻断剂，Ki为1.4 uM。
| Cas No.: |
328541-79-3 |
| 名称: |
N-(2-Naphthalenyl)-((3,5-dibromo-2,4-dihydroxyphenyl)methylene)glycinehydrazide |
| 别名: |
GlyH-101，Cystic Fibrosis Transmembrane Conductance Regulator Inhibitor II |
| SMILES: |
C(N/N=C/C1=CC(Br)=C(O)C(Br)=C1O)(=O)CNC1=CC=C2C(=C1)C=CC=C2 |
| 分子式: |
C19H15Br2N3O3 |
| 分子量: |
493.2 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
A cell-permeable glycinyl hydrazone compound that acts as a potent, selective and reversible open-channel blocker of CFTR with intermediate speed (< 1 min; 95% inhibition at 50 µM; Ki = 4.3 µM in CFTR-expressing FRT cells For apical membrane Cl- current) |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_1515_DC7039_328541-79-3 |
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COA
| LOT NO. |
DOWNLOAD |
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