L-006,235
产品编号: DC7934
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应用领域
N-[1-(cyanomethylcarbamoyl)cyclohexyl]-4-[2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-yl]benzamide
| Cas No.: |
294623-49-7 |
| 名称: |
N-[1-[[(Cyanomethyl)amino]carbonyl] cyclohexyl]-4-[2-(4-methyl-1-piperazinyl)-4-thiazo lyl]benzamide |
| 别名: |
L-006235,L 006235,L006235 |
| SMILES: |
CN1CCN(C2=NC(C3=CC=C(C(NC4(C(NCC#N)=O)CCCCC4)=O)C=C3)=CS2)CC1 |
| 分子式: |
C24H30N6O2S |
| 分子量: |
466.6 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| References: |
L-006,235 is a potent, reversible cathepsin K inhibitor (IC50 = 0.25 nM) that displays > 4000-fold selectivity over cathepsins B, L and S. Displays reduced selectivity in cell-based assays possibly due to lysosomal accumulation. Reduces collagen breakdown |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_2025_DC7934_294623-49-7 |
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COA
| LOT NO. |
DOWNLOAD |
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询盘
