MRS-1706

产品编号: DC12251 Featured
MRS-1706
结构式
264622-53-9
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中国地区超过5000个高品质化合物库存
应用领域
MRS-1706 是一种有效选择的 A2B 腺苷受体的反向激动剂。MRS-1706 对人 A2B、A2A、A1 和 A3 受体的 Ki 值分别为 1.39、112、157 和 230 nM。
Cas No.: 264622-53-9
名称:
别名: MRS-1706,MRS 1706,MRS1706
SMILES: O=C(NC1=CC=C(C(C)=O)C=C1)COC2=CC=C(C3=NC(N(CCC)C(N(CCC)C4=O)=O)=C4N3)C=C2
分子式: C27H29N5O5
分子量: 503.55
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: In Vitro MRS-1706 is a selective adenosine A2B receptor inverse agonist with Ki values of 1.39, 157, 112, and 230 nM for human A2B, A1, A2A, and A3 receptors, respectively. Pretreatment with ZM241385 (A2A-Ado receptor antagonist) alone or in combination with MRS-1706 (A2B-Ado receptor antagonist) results in a pure constriction upon adenosine.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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