AICAR (Acadesine)
产品编号: DC7047
我们的合作伙伴:
中国地区超过5000个高品质化合物库存
应用领域
Acadesine results in accumulation of ZMP, which mimics the stimulating effect of AMP on AMPK and AMPK kinase. Phase 3.
Cas No.: |
2627-69-2 |
名称: |
5-amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-1H-imidazole-4-carboxamide |
别名: |
AICAR (Acadesine) |
SMILES: |
O[C@H]([C@@H]1O)[C@@H](O[C@@H]1CO)N(C=N2)C(N)=C2C(N)=O |
分子式: |
C9H14N4O5 |
分子量: |
258.23 |
纯度: |
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保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: |
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In Vivo: |
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In Vitro: |
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References: |
Acadesine (500 μM) increases the ZMP content in extracts of isolated hepatocytes after up to 30-40 min treatment, then remains fairly constant at approximately 4 nmol/g. Acadesine (500 μM) causes a transient 12-fold activation of AMPK at 15 min in rat hep |
Kinase Assay: |
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Cell Assay: |
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Animal Administration: |
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References: |
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MSDS
COA
LOT NO. |
DOWNLOAD |
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2018-0101 |
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