| Cas No.: | 252917-06-9 |
| 名称: | 6-(2-(4-(2,4-dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-ylamino)ethylamino)nicotinonitrile hydrochloride |
| 别名: | CHIR 99021, CT 99021,CHIR99021,CT-99021 |
| SMILES: | CC1=CN=C(N1)C2=CN=C(N=C2C3=C(C=C(C=C3)Cl)Cl)NCCNC4=NC=C(C=C4)C#N |
| 分子式: | C22H18Cl2N8 |
| 分子量: | 465.34 |
| 纯度: | |
| 保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | |
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| References: | CHIR-99021 (CT99021) is a glycogen synthase kinase 3β (GSK3β) inhibitor that has antiproliferative activity in vitro and in vivo. CHIR-99021 inhibits GSK-3 with IC50 at 7 nM. In a series of carcinoma cell lines, the IC50 of CHIR99021 For proliferation is about 10μM. For the detailed information about the solubility of CHIR-99021 (CT99021) in water, the solubility of CHIR-99021 (CT99021) in DMSO, the solubility of CHIR-99021 (CT99021) in PBS buffer, the animal experiment（test） of CHIR-99021 (CT99021),the in vivo,in vitro and clinical trial test of CHIR-99021 (CT99021),the cell experiment（test） of CHIR-99021 (CT99021),the IC50, EC50 and Affinity of CHIR-99021 (CT99021), please contact DC Chemicals. |
| Kinase Assay: | |
| Cell Assay: | |
| Animal Administration: | |
| References: |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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