LFM-A13
产品编号: DC7937
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应用领域
LFM-A13 是一种有效的 BTK,JAK2,PLK 抑制剂,可抑制 BTK,Plx1 和 PLK3 的活性,IC50 分别为 2.5 μM,10 μM 和 61 μM。
Cas No.: |
244240-24-2 |
名称: |
2Z-cyano-N-(2,5-dibromophenyl)3-hydroxy-2-butenamide |
别名: |
LFMA13 |
SMILES: |
C(NC1=CC(Br)=CC=C1Br)(=O)/C(/C#N)=C(\O)/C |
分子式: |
C11H8Br2N2O2 |
分子量: |
360 |
纯度: |
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保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: |
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In Vivo: |
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In Vitro: |
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References: |
Bruton’s tyrosine kinase (BTK) is a member of the BTK/Tec family of protein tyrosine kinases involved in signal transduction pathways regulating growth and differentiation of B-cells. BTK acts as an inhibitor of Fas/APO-1-mediated apoptosis in B-cells by |
Kinase Assay: |
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Cell Assay: |
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Animal Administration: |
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References: |
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MSDS
TITLE |
DOWNLOAD |
MSDS_2028_DC7937_244240-24-2 |
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COA
LOT NO. |
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