Tosedostat (CHR2797)

产品编号: DC8116
Tosedostat (CHR2797)
结构式
238750-77-1
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中国地区超过5000个高品质化合物库存
应用领域
CHR-2797 is an aminopeptidase inhibitor, with IC50 values of 100 nM for LAP3 (LAP), 150 nM for PSAP (PuSA) and 220 nM for CD13 (Aminopeptidase N).
Cas No.: 238750-77-1
名称: alpha-[[(2R)-2-[(1S)-1-Hydroxy-2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]amino]benzeneacetic acid cyclopentyl ester
别名: CHR 2797,CHR-2797
SMILES: O=C(OC1CCCC1)[C@@H](NC([C@@H]([C@H](O)C(NO)=O)CC(C)C)=O)C2=CC=CC=C2
分子式: C21H30N2O6
分子量: 406.47
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: CHR-2797 is an aminopeptidase inhibitor, with IC50 values of 100 nM for LAP3 (LAP), 150 nM for PSAP (PuSA) and 220 nM for CD13 (Aminopeptidase N). CHR-2797 is converted in cells to the active acid metabolite, CHR-79888, which is a significant inhibitor of Leukotriene A4 hydrolase with an IC50 of 8 nM. CHR-2797 exhibits profound anti-proliferative effects against a range of cancer cell lines such as U-937, HL-60, KG-1 and GDM-1. For the detailed information of Tosedostat (CHR2797), the solubility of Tosedostat (CHR2797) in water, the solubility of Tosedostat (CHR2797) in DMSO, the solubility of Tosedostat (CHR2797) in PBS buffer, the animal experiment (test) of Tosedostat (CHR2797), the cell expriment (test) of Tosedostat (CHR2797), the in vivo, in vitro and clinical trial test of Tosedostat (CHR2797), the EC50, IC50,and affinity,of Tosedostat (CHR2797), For the detailed information of Tosedostat (CHR2797), the solubility of Tosedostat (CHR2797) in water, the solubility of Tosedostat (CHR2797) in DMSO, the solubility of Tosedostat (CHR2797) in PBS buffer, the animal experiment (test) of Tosedostat (CHR2797), the cell expriment (test) of Tosedostat (CHR2797), the in vivo, in vitro and clinical trial test of Tosedostat (CHR2797), the EC50, IC50,and affinity,of Tosedostat (CHR2797), Please contact DC Chemicals.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
TITLE DOWNLOAD
MSDS_3468_DC8116_238750-77-1
COA
LOT NO. DOWNLOAD
产品编号 产品名称 应用领域
DC8116 Tosedostat (CHR2797) CHR-2797 is an aminopeptidase inhibitor, with IC50 values of 100 nM for LAP3 (LAP), 150 nM for PSAP (PuSA) and 220 nM for CD13 (Aminopeptidase N).