EED-226

产品编号: DC10017 Featured
EED-226
结构式
2083627-02-3
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中国地区超过5000个高品质化合物库存
应用领域
EED226 是一种多梳抑制复合物 2 (PRC2) 抑制剂,与胚胎外胚层发育 (EED) 上的 K27me3 口袋结合,在移植瘤小鼠模型中具有强的抗肿瘤活性。EED226 是一种有效的,口服可生物利用的,选择性 EED 抑制剂。当 H3K27me0 肽用作体外酶法测定的底物时,EED226 抑制 PRC2 的 IC50 为 23.4 nM。
Cas No.: 2083627-02-3
名称:
别名: EED226,EED 226
SMILES: CS(=O)(=O)C1=CC=C(C=C1)C2=CN=C(N3C2=NN=C3)NCC4=CC=CO4
分子式: C17H15N5O3S
分子量: 369.08
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References:
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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