MDVN1003

产品编号: DC10650 Featured
MDVN1003
结构式
2058116-52-0
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中国地区超过5000个高品质化合物库存
应用领域
MDVN1003是BTK和PI3Kδ的有效抑制剂。
Cas No.: 2058116-52-0
名称:
别名: MDVN1003; MDVN-1003; MDVN 1003
SMILES: NC1=C2C(N(C3CC(C=CC(N)=C4)=C4C3)N=C2C5=CC(NCCO6)=C6C(F)=C5)=NC=N1
分子式: C22H20FN7O
分子量: 417.44
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: MDVN1003 is a potent inhibitor of BTK amd PI3K delta. MDVN1003 inhibits Bruton's tyrosine kinase (BTK) and phosphatidylinositol-3-kinase delta (PI3Kδ), two proteins regulated by the B cell receptor (BCR) that drive the growth of many NHLs. MDVN1003 induces cell death in a B cell lymphoma cell line but not in an irrelevant erythroblast cell line.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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