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Irreversible inhibitor of TNF-α-stimulated IκBα phosphorylation (IC50 ~ 10 μM); leads to decreased NF-κB and subsequent decreased expression of adhesion molecules. Also reversibly activates MAP kinases and stimulates apoptosis. Anti-inflammatory in vivo. For the detailed information of Bay 11-7085, the solubility of Bay 11-7085 in water, the solubility of Bay 11-7085 in DMSO, the solubility of Bay 11-7085 in PBS buffer, the animal experiment (test) of Bay 11-7085, the cell expriment (test) of Bay 11-7085, the in vivo, in vitro and clinical trial test of Bay 11-7085, the EC50, IC50,and affinity,of Bay 11-7085, Please contact DC Chemicals. |