Cas No.: | 193551-21-2 |
名称: | |
别名: | SB-239063; SB239063 |
SMILES: | COC1=NC=CC(C2=C(N=CN2[C@H]3CC[C@H](O)CC3)C4=CC=C(F)C=C4)=N1 |
分子式: | C20H21FN4O2 |
分子量: | 368.4 |
纯度: | |
保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | |
In Vivo: | |
In Vitro: | |
References: | SB 239063 is a potent and selective p38 MAPK inhibitor (IC50 = 44 nM for p38α). SB 239063 displays > 220-fold selectivity over ERK, JNK1 and other kinases; ~ 3-fold more selective than SB 203580. IC50 value: 44 nM ( p38α) Target: p38 MAPK SB 239063 redu |
Kinase Assay: | |
Cell Assay: | |
Animal Administration: | |
References: |