Cas No.: | 1923773-01-6 |
名称: | 6-(4-methylpiperazin-1-yl)-3-(naphthalen-2-yl)-4-(pyridin-4-yl)pyridazine hydrochloride |
别名: | MW01-18-150SRM;MW 150;MW150 |
SMILES: | C(C1=CC=C2C(=C1)C=CC=C2)1=NN=C(N2CCN(C)CC2)C=C1C1C=CN=CC=1.[H]Cl |
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保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
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References: | A novel potent, selective, CNS penetrant and orally active inhibitor of p38α MAPK with Ki of 101 nM; effectively suppresses hippocampal-dependent associative and spatial memory deficits in synaptic dysfunction mouse models; also can selectively modulate neuroinflammatory responses associated with pathology progression. |
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