Cas No.: | 1903008-80-9 |
名称: | N-{5-[(4-{4-[(dimethylamino)methyl]-3-phenyl-1H-pyrazol-1-yl}pyrimidin-2-yl)amino]-4-methoxy-2-(morpholin-4-yl)phenyl}prop-2-enamide |
别名: | YH 25448;YH25448;GNS-1480;GNS1480 |
SMILES: | C(NC1=CC(NC2=NC=CC(N3C=C(CN(C)C)C(C4=CC=CC=C4)=N3)=N2)=C(OC)C=C1N1CCOCC1)(=O)C=C |
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保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
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References: | Lazertinib (YH25448, GNS-1480) is a highly potent, mutant-selective, irreversible, brain-penetrant and orally active EGFR tyrosine-kinase inhibitors for both the T790M mutation and activating EGFR mutations; shows the beneficial for the NSCLC with brain metastasis. |
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