ROSCOVITINE(Seliciclib)
产品编号: DC4124
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应用领域
Seliciclib (Roscovitine) 是一种口服有效的,选择性的 CDKs 抑制剂,抑制 CDK5,Cdc2 和 CDK2 的 IC50 分别为0.2 μM,0.65 μM,0.7 μM。
Cas No.: |
186692-46-6 |
名称: |
(R)-2-(6-(benzylamino)-9-isopropyl-9H-purin-2-ylamino)butan-1-ol |
别名: |
Seliciclib |
SMILES: |
CC[C@H](CO)NC1=NC2=C(C(=N1)NCC3=CC=CC=C3)N=CN2C(C)C |
分子式: |
C19H26N6O |
分子量: |
354.45 |
纯度: |
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保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: |
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In Vivo: |
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In Vitro: |
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References: |
Description of Seliciclib: Seliciclib is an orally bioavailable, small-molecule cyclin-dependent kinase (CDK) inhibitor with potential proapoptotic and antineoplastic activities. Seliciclib primarily inhibits CDK2/E, CDK2/A, CDK7 and CDK9 by competing Fo |
Kinase Assay: |
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Cell Assay: |
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Animal Administration: |
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References: |
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MSDS
COA
LOT NO. |
DOWNLOAD |
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2018-0101 |
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