SPHINX31
产品编号: DC11369
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应用领域
SPHINX31 是有效的、丝氨酸/富含精氨酸的蛋白激酶1 (SRPK1) 的选择性抑制剂，其IC50 值为5.9 nM。SPHINX31能够抑制丝氨酸/丰富精氨酸的剪接因子1 (SRSF1)的磷酸化。SPHINX31是一种潜在的局部治疗新生血管性眼病的药物。
| Cas No.: |
1818389-84-2 |
| 名称: |
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| 别名: |
SPHINX31 |
| SMILES: |
O=C(C1=CC=C(C2=CC=NC=C2)O1)NC(C=C(C(F)(F)F)C=C3)=C3N(CC4)CCN4CC5=CC=CC=N5 |
| 分子式: |
C27H24F3N5O2 |
| 分子量: |
507.5 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50 = 5.9 nM).It is selective for SRPK1 over a panel of 50 kinases at a concentration of 1 μM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SR |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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询盘
