Centrinone-B
产品编号: DC10011
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应用领域
Centrinone-B (LCR-323) 是一种有效的,高度选择性的 PLK4 抑制剂,Ki 值为 0.59 nM。
Cas No.: |
1798871-31-4 |
名称: |
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别名: |
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SMILES: |
CC1=CC(=NN1)NC2=NC(=NC(=C2OC)N3CCCCC3)SC4=C(C=C(C=C4)S(=O)(=O)CC5=C(C(=CC=C5)[N+](=O)[O-])F)F |
分子式: |
C27H27F2N7O5S2 |
分子量: |
631.67 |
纯度: |
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保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: |
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In Vitro: |
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References: |
Centrinone-B is a high affinity and selective PLK4 inhibitor (Ki = 0.59 nM).
Centrinone-B is a selective and reversible inhibitor of polo-like kinase 4 (Plk4). Centrinone-B exhibits >2000-fold selectivity for PLK4 over Aurora A and Aurora B. |
Kinase Assay: |
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Cell Assay: |
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Animal Administration: |
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References: |
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MSDS
COA
LOT NO. |
DOWNLOAD |
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2018-0101 |
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