| Cas No.: | 179248-59-0 |
| 名称: | 6,7-dimethoxy-N-(4-phenoxyphenyl)-4-quinazolinamine |
| 别名: | Src I1 |
| SMILES: | COC1=C(OC)C=C(N=CN=C2NC3=CC=C(OC4=CC=CC=C4)C=C3)C2=C1 |
| 分子式: | C22H19N3O3 |
| 分子量: | 373.4 |
| 纯度: | |
| 保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | |
| In Vivo: | |
| In Vitro: | |
| References: | Src kinase inhibitor I is a potent competitive inhibitor of both Src and Lck (IC50 = 44 and 88 nM, respectively), as well as Csk and Yes.It less effectively blocks the receptor tyrosine kinases VEGFR2 and C-fms (IC50 = 0.32 and 30 µM), as well as a long list of serine/threonine kinases.Src Kinase Inhibitor I also inhibits receptor-interacting protein-2 with an IC50 value of 26 nM. |
| Kinase Assay: | |
| Cell Assay: | |
| Animal Administration: | |
| References: |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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