TA-01
产品编号: DC9301
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应用领域
TA-01 是一种有效的 CK1 和 p38 MAPK 抑制剂,对 CK1ε,CK1δ 和 p38 MAPK 的 IC50 值分别为 6.4 nM,6.8 nM 和 6.7 nM。
Cas No.: |
1784751-18-3 |
名称: |
4-(2-(2,6-Difluorophenyl)-4-(fluorophenyl)-1H-imidazol-5-yl)pyridine |
别名: |
TA-01,TA01,TA 01 |
SMILES: |
C(C1NC(C2=CC=NC=C2)=C(C2=CC=C(F)C=C2)N=1)1=C(F)C=CC=C1F |
分子式: |
C20H12F3N3 |
分子量: |
351.32 |
纯度: |
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保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: |
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In Vivo: |
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In Vitro: |
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References: |
TA-01 induces cardiomyocyte differentiation from human embryonic stem cells following mesoderm induction at 1 μM. Inhibits cardiomyocyte differentiation at 5 μM. Potently inhibits CK1ε, p38α, and CK1δ (IC50 values are 6.4, 6.7 and 6.8 nM respectively). |
Kinase Assay: |
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Cell Assay: |
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Animal Administration: |
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References: |
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MSDS
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MSDS_2625_DC9301_1784751-18-3 |
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