YC-1(Lificiguat)
产品编号: DC7720
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应用领域
Lificiguat 结合到 可溶性鸟苷酸环化酶(sGC)的β亚基,在CO存在条件下,Kd 为 0.6-1.1 μM。
Cas No.: |
170632-47-0 |
名称: |
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别名: |
Lificiguat; YC 1 |
SMILES: |
C1=CC=C(C=C1)CN2C3=CC=CC=C3C(=N2)C4=CC=C(O4)CO |
分子式: |
C19H16N2O2 |
分子量: |
304.34 |
纯度: |
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保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: |
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In Vivo: |
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In Vitro: |
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References: |
YC-1(Lificiguat) is a soluble guanylyl cyclase(sGC) activator; binds to the heme-containing domain of the β subunit with Kd value of 0.6-1.1 μM in the presence of CO.
in vitro: YC-1 and related compounds stimulate sGC both independently and synergisticall |
Kinase Assay: |
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Cell Assay: |
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Animal Administration: |
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References: |
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MSDS
COA
LOT NO. |
DOWNLOAD |
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2018-0101 |
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