LY335979 (Zosuquidar 3HCl)

产品编号: DC2018 Featured
LY335979 (Zosuquidar 3HCl)
结构式
167465-36-3
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中国地区超过5000个高品质化合物库存
应用领域
Zosuquidar trihydrochloride是P-糖蛋白的抑制剂, Ki值为59 nM。
Cas No.: 167465-36-3
名称: 1-Piperazineethanol, 4-[(1aα,6α,10bα)-1,1-difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-yl]-α-[(5-quinolinyloxy)methyl]-,trihydrochloride
别名: RS-33295-198, Zosuquidar, LY-335979
SMILES: C1CN(CCN1C[C@H](COC2=CC=CC3=C2C=CC=N3)O)C4C5=CC=CC=C5[C@H]6[C@H](C6(F)F)C7=CC=CC=C47.Cl.Cl.Cl
分子式: C32H31F2N3O2.3HCl
分子量: 636.99
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: Description of Zosuquidar: Zosuquidar is a potent P-glycoprotein inhibitor, which binds with high affinity to P-glycoprotein and inhibits P-glycoprotein-mediated multidrug resistance (MDR). P-glycoprotein, encoded by the MDR-1 gene, is a member of the ATP-binding cassette superfamily of transmembrane transporters and prevents the intracellular accumulation of many natural product-derived cytotoxic agents. Check For active clinical trials or closed clinical trials using this agent. (NCI Thesaurus). For the detailed information about the solubility of LY335979 (Zosuquidar 3HCl) in water, the solubility of LY335979 (Zosuquidar 3HCl) in DMSO, the solubility of LY335979 (Zosuquidar 3HCl) in PBS buffer, the animal experiment(test) of LY335979 (Zosuquidar 3HCl),the in vivo,in vitro and clinical trial test of LY335979 (Zosuquidar 3HCl),the cell experiment(test) of LY335979 (Zosuquidar 3HCl),the IC50, EC50 and Affinity of LY335979 (Zosuquidar 3HCl), please contact DC Chemicals.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
TITLE DOWNLOAD
MSDS_993_DC2018_167465-36-3
COA
LOT NO. DOWNLOAD
产品编号 产品名称 应用领域
DC9813 Valspodar(PSC833) Valspodar是一种选择性的P-糖蛋白抑制剂,已被用作实验性癌症治疗和化学增敏剂。
DC2018 LY335979 (Zosuquidar 3HCl) Zosuquidar trihydrochloride是P-糖蛋白的抑制剂, Ki值为59 nM。