SR9243

产品编号: DC8279 Featured
SR9243
结构式
1613028-81-1
此产品仅供科研所需,我们不出售给病人
​我们将匹配市场上最好的价格给您
Email:order@dcbio.cn
免费咨询电话:4008862077
我们的合作伙伴:
  • 20
  • 19
  • 18
  • 17
  • 16
  • 15
  • 14
  • 12
  • 11
  • 10
  • 9
  • 8
  • 13
  • 6
  • 5
  • 4
  • 3
  • 2
  • 1
中国地区超过5000个高品质化合物库存
应用领域
SR9243 是 liver-X-receptor (LXR) 的反向激动剂,能够诱导 LXR-辅阻遏物相互作用。
Cas No.: 1613028-81-1
名称: N-[2-(3-Bromo-phenyl)-ethyl]-N-(3'-methanesulfonyl-biphenyl-4-ylmethyl)-2,4,6-trimethyl-benzenesulfonamide
别名: SR 9243,SR9243,SR-9243
SMILES: CC1=CC(=C(C(=C1)C)S(=O)(=O)N(CCC2=CC(=CC=C2)Br)CC3=CC=C(C=C3)C4=CC(=CC=C4)S(=O)(=O)C)C
分子式: C31H32BrN04S2
分子量: 626.62
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: SR9243 is a new inhibitor of The nuclear receptor liver-X-receptor (LXR),inducing LXR-corepressor interaction. In cancer cells, SR9243 significantly inhibited the Warburg effect and lipogenesis by reducing glycolytic and lipogenic gene expression. SR9243 induced apoptosis in tumors without inducing weight loss, hepatotoxicity, or inflammation. For the detailed information of SR9243, the solubility of SR9243 in water, the solubility of SR9243 in DMSO, the solubility of SR9243 in PBS buffer, the animal experiment (test) of SR9243, the cell expriment (test) of SR9243, the in vivo, in vitro and clinical trial test of SR9243, the EC50, IC50,and affinity,of SR9243, For the detailed information of SR9243, the solubility of SR9243 in water, the solubility of SR9243 in DMSO, the solubility of SR9243 in PBS buffer, the animal experiment (test) of SR9243, the cell expriment (test) of SR9243, the in vivo, in vitro and clinical trial test of SR9243, the EC50, IC50,and affinity,of SR9243, Please contact DC Chemicals.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
产品编号 产品名称 应用领域
DC8279 SR9243 SR9243 是 liver-X-receptor (LXR) 的反向激动剂,能够诱导 LXR-辅阻遏物相互作用。
DC12048 SR9238 SR9238 是一种合成的肝 X 受体 (LXR) 反向激动剂,对于 LXRα 和 LXRβ 的 IC50 值分别为 214 nM 和 43 nM。
DC11415 GSK2033 GSK2033 是一种 LXR 拮抗剂,对于 LXRα 和 LXRβ 的 pIC50 值分别为 7 和 7.4。