Cas No.: | 1610759-22-2 |
名称: | N-cyclopropyl-4-(7-((((1s,3s)-3-hydroxy-3-methylcyclobutyl)methyl)amino)-5-(pyridin-2-yloxy)pyrazolo[1,5-a]pyridin-3-yl)-2-methylbenzamide |
别名: | CFI402257,CFI 402257,CFI-402257 |
SMILES: | C1=CC=CC(OC2=CC3=C(C4=CC=C(C(NC5CC5)=O)C(C)=C4)C=NN3C(NC[C@H]3C[C@@](C)(O)C3)=C2)=N1 |
分子式: | C29H31N5O3 |
分子量: | 497.2 |
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保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | |
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References: | CFI-402257 is a highly potent and selective TTK (threonine tyrosine kinase) Inhibitor ((TTK Ki = 0.1 nM) with potential anticancer activity. TTK is an essential chromosomal regulator and is overexpressed in aneuploid tumors. High TTK levels correlate with |
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