TH 588
产品编号: DC7726
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应用领域
TH588 是 MTH1 (NUDT1) 高效选择性抑制剂，IC50 值 5 nM。
| Cas No.: |
1609960-31-7 |
| 名称: |
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| 别名: |
TH 588,TH-588,TH588 |
| SMILES: |
C1CC1NC2=NC(=NC(=C2)C3=C(C(=CC=C3)Cl)Cl)N |
| 分子式: |
C13H12Cl2N4 |
| 分子量: |
295.17 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
First-in-class MTH1 inhibitor (IC50 value 5.0 nM) that selectively and effectively kills U2OS and other cancer cell lines, with considerably less toxicity towards several primary or immortalized cells. Similar to TH 287, TH 588 shows no relevant inhibitor |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_1929_DC7726_1609960-31-7 |
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COA
| LOT NO. |
DOWNLOAD |
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