Cas No.: | 1608125-21-8 |
名称: | |
别名: | AMG-319,AMG 319,AMG319 |
SMILES: | C[C@H](NC1=C2N=CNC2=NC=N1)C3=CC4=CC=C(F)C=C4N=C3C5=NC=CC=C5 |
分子式: | C21H16FN7 |
分子量: | 385.4 |
纯度: | |
保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | |
In Vivo: | |
In Vitro: | |
References: | AMG 319 is an investigational, highly selective, small molecule inhibitor of PI3Kδ that blocks B cell proliferation following BCR stimulation both in vitro and in vivo, inhibits basal AKT phosphorylation, and inhibits proliferation in lymphoid tumor cells. |
Kinase Assay: | |
Cell Assay: | |
Animal Administration: | |
References: |