EPZ011989
产品编号: DC7927
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应用领域
EPZ011989是EZH2高效选择性且口服型抑制剂，对wt EZH2以及EZH2突变型Ki值<3nM。
| Cas No.: |
1598383-40-4 |
| 名称: |
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| 别名: |
EPZ011989,EPZ-011989 |
| SMILES: |
C(C(=O)NCC1=C(C)C=C(C)NC1=O)1=C(C)C(N([C@@H]2CC[C@@H](N(CCOC)C)CC2)CC)=CC(C#CCN2CCOCC2)=C1 |
| 分子式: |
C35H51N504 |
| 分子量: |
605.4 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
EPZ011989 demonstrates significant tumor growth inhibition in a mouse xenograft model of human B cell lymphoma.EPZ011989, that equipotently inhibits mutant and wild-type EZH2 with an inhibition constant (Ki) of <3 nM. EPZ011989 is also a specific EZH2 inh |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_2019_DC7927_1598383-40-4 |
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COA
| LOT NO. |
DOWNLOAD |
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询盘
