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应用领域
LY303511, an inactive analogue of LY294002, is a mTOR inhibitor that did not inhibit PI3-K.
Cas No.: |
154447-38-8 |
名称: |
2-(1-Piperazinyl)-8-phenyl-4H-1-benzopyran-4-one |
别名: |
LY 303511; LY303511 |
SMILES: |
O=C1C2=C(OC(N3CCNCC3)=C1)C(C4=CC=CC=C4)=CC=C2 |
分子式: |
C19H18N2O2 |
分子量: |
306.36 |
纯度: |
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保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: |
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In Vivo: |
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In Vitro: |
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References: |
Negative control compound with respect to LY 294002 (Cat. No. 1130) PI 3-kinase inhibitory activity. Blocks voltage-gated potassium (Kv) channels (IC50 = 64.6 μM) and inhibits IL-1β-stimulated NF-κB activation, attenuating MCP-1 expression. Antiproliferat |
Kinase Assay: |
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Cell Assay: |
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Animal Administration: |
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References: |
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MSDS
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MSDS_3415_DC7210_154447-38-8 |
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