Cas No.: | 1527473-33-1 |
名称: | 3-[4-(4-Morpholinyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-benzonitrile |
别名: | PF 06447475,PF06447475 |
SMILES: | C1COCCN1C2=NC=NC3=C2C(=CN3)C4=CC=CC(=C4)C#N |
分子式: | C17H15N5O |
分子量: | 305.33 |
纯度: | |
保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | |
In Vivo: | |
In Vitro: | |
References: | PF-06447475 was sufficiently potent in the LRRK2 whole cell assay (WCA; IC50=25 nM) (pS935 end point) to warrant additional profiling. Oral administration of PF-06447475 twice daily for 15 days was well tolerated at doses up to 60 mg kg-1 day-1 (31-fold C |
Kinase Assay: | |
Cell Assay: | |
Animal Administration: | |
References: |