EMA400

产品编号: DC10870 Featured
EMA400
结构式
152362-51-1
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中国地区超过5000个高品质化合物库存
应用领域
EMA400是一种有效且高选择性的AT2R拮抗剂。
Cas No.: 152362-51-1
名称:
别名: EMA400; EMA 400; EMA-400; PD-126055; PD126055; PD 126055,152362-51-1
SMILES: O=C(C1N(C(C(C2=CC=CC=C2)C3=CC=CC=C3)=O)CC4=C(C(OCC5=CC=CC=C5)=C(OC)C=C4)C1)O
分子式: C32H29NO5
分子量: 507.59
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: EMA401, a highly selective AT2R antagonist, inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons. target: AT2R In vivo: AngII induces p38, p42/p44 mitogen activated protein kinase (MAPK) activation, neurite outgrowth in adult rat DRG neurons, and sensitization of adult rat and human DRG neurons that is blocked by EMA401. Inhibits capsaicin responses in cultured hDRG neurons.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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