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Alvocidib is a synthetic N-methylpiperidinyl chlorophenyl flavone compound. As an inhibitor of cyclin-dependent kinase, alvocidib induces cell cycle arrest by preventing phosphorylation of cyclin-dependent kinases (CDKs) and by down-regulating cyclin D1 and D3 expression, resulting in G1 cell cycle arrest and apoptosis. This agent is also a competitive inhibitor of adenosine triphosphate activity. Check For active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
For the detailed information about the solubility of Flavopiridol in water, the solubility of Flavopiridol in DMSO, the solubility of Flavopiridol in PBS buffer, the animal experiment(test) of Flavopiridol,the in vivo,in vitro and clinical trial test of Flavopiridol,the cell experiment(test) of Flavopiridol,the IC50, EC50 and Affinity of Flavopiridol, please contact DC Chemicals. |